Revolutionizing bioimaging
to elevate human health

With powerful end-to-end solutions for intact tissue spatial biology, LifeCanvas is transforming biomedical research, drug discovery, personalized medicine, and disease diagnoses.

Integrated solutions, sample-to-data processing, & expert support for an unparalleled range of applications.

From neuroscience to oncology, whole organs to organoids, LifeCanvas offers a unique end-to-end pipeline tailor-made for your research application. Our automated tools and proprietary technologies will streamline your workflow and improve your data outputs with unprecedented speed, accuracy, depth, and cost-effectiveness. We partner with you to obtain unbiased data that will drive your studies forward and enable breakthrough discoveries.

Sample Preparation

Optimize samples for imaging with advanced techniques for tissue preservation, tissue clearing, and immunolabeling.

Light Sheet Imaging

Easily capture 3D image data from a wide range of tissue types and sizes with unmatched acquisition speed and resolution.

3D Data Analysis

Leverage AI-powered cell detection algorithms to generate robust analysis outputs from 3D image data.

Recently published studies

Microglia regulate sleep through calcium-dependent modulation of norepinephrine transmission.

Chenyan Ma, Bing Li, Daniel Silverman, Xinlu Ding, Anan Li, Chi Xiao, Ganghua Huang, Kurtresha Worden, Sandra Muroy, Wei Chen, Zhengchao Xu, Chak Foon Tso, Yixuan Huang, Yufan Zhang, Qingming Luo, Kaoru Saijo & Yang Dan.

Journal:
Nature Neuroscience
Publication Date:
Research Area:
Neural Circuits, Other
Tissue Species:
Mouse
Tissue Type:
Brain, Heart
Products Cited:
SmartSPIM, CRO Services
Opioid-driven disruption of the septal complex reveals a role for neurotensin-expressing neurons in withdrawal

Rhiana C. Simon, Weston T. Fleming, Pranav Senthilkumar, Brandy A. Briones1,2, Kentaro K. Ishii, Madelyn M. Hjort, Madison M. Martin, Koichi Hashikawa, Andrea D. Sanders, Sam A. Golden, Garret D. Stuber.

Journal:
bioRxiv
Publication Date:
Research Area:
Neural Circuits, Other
Tissue Species:
Mouse
Tissue Type:
Brain, Heart
Products Cited:
SHIELD, EasyIndex, SmartClear, SmartSPIM
Fatal iatrogenic cerebral β-amyloid-related arteritis in a woman treated with lecanemab for Alzheimer’s disease

Elena Solopova, Wilber Romero-Fernandez, Hannah Harmsen, Lissa Ventura-Antunes, Emmeline Wang, Alena Shostak, Jose Maldonado, Manus J. Donahue, Daniel Schultz, Thomas M. Coyne, Andreas Charidimou & Matthew Schrag.

Journal:
Nature Communications
Publication Date:
Research Area:
Neurodegeneration
Tissue Species:
Human
Tissue Type:
Brain, Biopsy
Products Cited:
SmartSPIM

LifeCanvas Portraits: Conversations with researchers

LifeCanvas Portraits: Dr. Sam Centanni

Dr. Sam Centanni uses the LifeCanvas pipeline to investigate the neurobiological overlap between stress and predisposition to alcohol abuse, as well as long-term effects of alcohol on the brain.

LifeCanvas Portraits: Dr. Mike Taormina

Dr. Mike Taormina uses SmartSPIM light sheet microscopy to rapidly image whole mouse brains, streamlining workflows at the Allen Institute.

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